Spatial heterogeneity or non-stationarity has become a popular and necessary concern in exploring relationships between variables. In this regard, geographically weighted (GW) models provide a powerful collection of techniques in its quantitative description. We developed a user-friendly, highperformance and systematic software, named GWmodelS, to promote better and broader usages of such models. Apart from a variety of GW models, including GW descriptive statistics, GW regression models, and GW principal components analysis, data management and mapping tools have also been incorporated with well-designed interfaces. (c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).