DrugSim2DR: Predict Drug Functional Similarity to Drug Repurposing
A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
| Version: |
0.1.0 |
| Depends: |
R (≥ 3.6) |
| Imports: |
igraph, stats, pheatmap, ChemmineR, rvest, base, sp, tidyr, reshape2 |
| Suggests: |
knitr, rmarkdown |
| Published: |
2022-11-09 |
| Author: |
Junwei Han [aut, cre, cph],
Ji Li [aut],
Jiashuo Wu [aut] |
| Maintainer: |
Junwei Han <hanjunwei1981 at 163.com> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: |
no |
| CRAN checks: |
DrugSim2DR results |
Documentation:
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