POSTm: Phylogeny-Guided OTU-Specific Association Test for Microbiome
Data
Implements the Phylogeny-Guided Microbiome OTU-Specific Association
Test method, which boosts the testing power by adaptively borrowing
information from phylogenetically close OTUs (operational taxonomic units)
of the target OTU. This method
is built on a kernel machine regression framework and allows for flexible
modeling of complex microbiome effects, adjustments for covariates, and
can accommodate both continuous and binary outcomes.
| Version: |
1.2 |
| Depends: |
methods |
| Imports: |
CompQuadForm, ape |
| Suggests: |
multtest, rmarkdown, knitr |
| Published: |
2022-06-06 |
| Author: |
Caizhi Huang [aut],
Jung-Ying Tzeng [aut],
Shannon T. Holloway [aut, cre] |
| Maintainer: |
Shannon T. Holloway <shannon.t.holloway at gmail.com> |
| License: |
GPL-2 |
| NeedsCompilation: |
no |
| CRAN checks: |
POSTm results |
Documentation:
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