ThreeArmedTrials: Design and Analysis of Clinical Non-Inferiority or Superiority Trials with Active and Placebo Control

Design and analyze three-arm non-inferiority or superiority trials which follow a gold-standard design, i.e. trials with an experimental treatment, an active, and a placebo control. Method for the following distributions are implemented: Poisson (Mielke and Munk (2009) <arXiv:0912.4169>), negative binomial (Muetze et al. (2016) <doi:10.1002/sim.6738>), normal (Pigeot et al. (2003) <doi:10.1002/sim.1450>; Hasler et al. (2009) <doi:10.1002/sim.3052>), binary (Friede and Kieser (2007) <doi:10.1002/sim.2543>), nonparametric (Muetze et al. (2017) <doi:10.1002/sim.7176>), exponential (Mielke and Munk (2009) <arXiv:0912.4169>).

Version:	1.0-4
Depends:	R (≥ 3.0.0)
Imports:	stats, MASS, methods, numDeriv
Suggests:	testthat, knitr, rmarkdown
Published:	2022-12-16
Author:	Tobias Mütze [aut, cre], Tim Friede [ctb]
Maintainer:	Tobias Mütze <tobias.muetze at outlook.com>
BugReports:	https://github.com/tobiasmuetze/ThreeArmedTrials/issues
License:	GPL (≥ 3)
URL:	https://github.com/tobiasmuetze/ThreeArmedTrials
NeedsCompilation:	yes
Materials:	NEWS
In views:	CausalInference, ClinicalTrials, ExperimentalDesign
CRAN checks:	ThreeArmedTrials results

Documentation:

Reference manual:	ThreeArmedTrials.pdf
Vignettes:	An introduction to planning and analyzing three-arm trials using the package ThreeArmedTrials

Downloads:

Package source:	ThreeArmedTrials_1.0-4.tar.gz
Windows binaries:	r-devel: ThreeArmedTrials_1.0-4.zip, r-release: ThreeArmedTrials_1.0-4.zip, r-oldrel: ThreeArmedTrials_1.0-4.zip
macOS binaries:	r-release (arm64): ThreeArmedTrials_1.0-4.tgz, r-oldrel (arm64): ThreeArmedTrials_1.0-4.tgz, r-release (x86_64): ThreeArmedTrials_1.0-4.tgz, r-oldrel (x86_64): ThreeArmedTrials_1.0-4.tgz
Old sources:	ThreeArmedTrials archive

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