Facilities for running simulations from ordinary
    differential equation ('ODE') models, such as pharmacometrics and other
    compartmental models.  A compilation manager translates the ODE model
    into C, compiles it, and dynamically loads the object code into R for
    improved computational efficiency.  An event table object facilitates
    the specification of complex dosing regimens (optional) and sampling
    schedules.  NB: The use of this package requires both C and
    Fortran compilers, for details on their use with R please see
    Section 6.3, Appendix A, and Appendix D in the "R Administration and
    Installation" manual. Also the code is mostly released under GPL.  The
    'VODE' and 'LSODA' are in the public domain.  The information is available
    in the inst/COPYRIGHTS. 
| Version: | 
2.0.11 | 
| Depends: | 
R (≥ 4.0.0) | 
| Imports: | 
PreciseSums (≥ 0.3), Rcpp (≥ 0.12.3), backports, cli (≥
2.0.0), checkmate, ggplot2, inline, lotri (≥ 0.4.0), magrittr, memoise, methods, rex, sys, tools, utils, rxode2ll (≥ 2.0.9), rxode2et (≥ 2.0.9), rxode2parse (≥ 2.0.12), rxode2random (≥
2.0.9), data.table (≥ 1.12.4), qs | 
| LinkingTo: | 
rxode2parse (≥ 2.0.12), rxode2random, rxode2et, PreciseSums (≥ 0.3), Rcpp, RcppArmadillo (≥ 0.9.300.2.0), BH | 
| Suggests: | 
Matrix, DT, covr, crayon, curl, digest, dplyr (≥ 0.8.0), ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr (≥ 1.0), withr, xgxr, pillar, tibble, units (≥ 0.6-0), rsconnect, devtools, patchwork, nlmixr2data, lifecycle | 
| Published: | 
2022-11-01 | 
| Author: | 
Matthew L. Fidler  
    [aut, cre],
  Melissa Hallow [aut],
  Wenping Wang [aut],
  Zufar Mulyukov [ctb],
  Alan Hindmarsh [ctb],
  Arun Srinivasan [ctb],
  Awad H. Al-Mohy [ctb],
  Cleve Moler [ctb],
  Drew Schmidt [ctb],
  Ernst Hairer [ctb],
  Gerhard Wanner [ctb],
  Gilbert Stewart [ctb],
  Goro Fuji [ctb],
  Hadley Wickham [ctb],
  Jack Dongarra [ctb],
  Jim Bunch [ctb],
  Linda Petzold [ctb],
  Martin Maechler [ctb],
  Matt Dowle [ctb],
  Matteo Fasiolo [ctb],
  Morwenn [ctb],
  Nicholas J. Higham [ctb],
  Roger B. Sidje [ctb],
  Simon Frost [ctb],
  Yu Feng [ctb] | 
| Maintainer: | 
Matthew L. Fidler  <matthew.fidler at gmail.com> | 
| BugReports: | 
https://github.com/nlmixr2/rxode2/issues/ | 
| License: | 
GPL (≥ 3) | 
| Copyright: | 
see file COPYRIGHTS | 
| URL: | 
https://nlmixr2.github.io/rxode2/,
https://github.com/nlmixr2/rxode2/ | 
| NeedsCompilation: | 
yes | 
| Language: | 
en-US | 
| Citation: | 
rxode2 citation info  | 
| Materials: | 
README NEWS  | 
| In views: | 
HighPerformanceComputing, MixedModels, Pharmacokinetics | 
| CRAN checks: | 
rxode2 results |