segregatr: Segregation Analysis for Variant Interpretation
An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>, and further popularised by Bayrak-Toydemir et al. (2008) <doi:10.1016/j.yexmp.2008.03.006>. This implementation allows custom penetrance values and liability classes, and includes specialised pedigree visualisations.
| Version: | 0.2.0 |
| Depends: | pedtools |
| Imports: | pedprobr |
| Suggests: | testthat (≥ 2.1.0) |
| Published: | 2021-04-15 |
| Author: | Magnus Dehli Vigeland
 [aut, cre] |
| Maintainer: | Magnus Dehli Vigeland <m.d.vigeland at medisin.uio.no> |
| BugReports: | https://github.com/magnusdv/segregatr/issues |
| License: | GPL-3 |
| URL: | https://github.com/magnusdv/segregatr |
| NeedsCompilation: | no |
| Language: | en-GB |
| Materials: | README NEWS |
| CRAN checks: | segregatr results |
Documentation:
| Reference manual: | segregatr.pdf |
Downloads:
| Package source: | segregatr_0.2.0.tar.gz |
| Windows binaries: | r-devel: segregatr_0.2.0.zip, r-release: segregatr_0.2.0.zip, r-oldrel: segregatr_0.2.0.zip |
| macOS binaries: | r-release (arm64): segregatr_0.2.0.tgz, r-oldrel (arm64): segregatr_0.2.0.tgz, r-release (x86_64): segregatr_0.2.0.tgz, r-oldrel (x86_64): segregatr_0.2.0.tgz |
Reverse dependencies:
| Reverse imports: | pedsuite |
Linking:
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